Fosaprepitant

From WikiMD.org
Jump to navigation Jump to search

Fosaprepitant

Fosaprepitant (pronounced foh-sa-PREP-i-tant) is a medication used in the prevention of chemotherapy-induced nausea and vomiting. It is a member of the neurokinin 1 (NK1) receptor antagonists class of drugs.

Etymology

The name "Fosaprepitant" is derived from its chemical structure. "Fos" refers to the phosphate group in its structure, "aprepitant" is the name of the active metabolite.

Pharmacology

Fosaprepitant is a prodrug of aprepitant, meaning it is metabolized in the body to become the active drug aprepitant. It works by blocking the action of substance P, a neurotransmitter in the brain that plays a key role in triggering nausea and vomiting.

Usage

Fosaprepitant is used in combination with other medications to prevent nausea and vomiting caused by chemotherapy. It is usually given before chemotherapy and works by blocking the action of substance P in the brain, which helps to reduce these side effects.

Related Terms

External links

Esculaap.svg

This WikiMD article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski