Casopitant
Casopitant (pronounced as ka-SO-pi-tant) is a drug that is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is a member of the drug class known as neurokinin 1 (NK1) receptor antagonists.
Etymology
The term Casopitant is derived from the Latin word casus, meaning fall or accident, and pitan, a term used in pharmacology to denote a substance that blocks or inhibits a biological action. Thus, Casopitant can be interpreted as a substance that blocks or inhibits the action of the NK1 receptor, which is involved in the induction of nausea and vomiting.
Pharmacology
Casopitant is a highly selective and potent antagonist of the human substance P/neurokinin 1 (NK1) receptor. It works by blocking the action of substance P, a neurotransmitter in the brain that plays a key role in the vomiting reflex. By blocking the action of substance P, casopitant can prevent and treat nausea and vomiting caused by chemotherapy.
Related Terms
See Also
References
External links
- Medical encyclopedia article on Casopitant
- Wikipedia's article - Casopitant
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