Befetupitant
Befetupitant
Befetupitant (pronunciation: be-fe-tu-pi-tant) is a potent and selective neurokinin 1 receptor antagonist used in the treatment of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).
Etymology
The term "Befetupitant" is derived from the combination of its chemical properties and its therapeutic use. "Be" refers to its chemical structure as a benzyl derivative, "fe" signifies its phenyl group, "tu" indicates its therapeutic use as a tachykinin antagonist, and "pitant" is a common suffix for neurokinin 1 receptor antagonists.
Pharmacology
Befetupitant acts by blocking the neurokinin 1 receptor, thus preventing the binding of substance P, a neuropeptide involved in pain perception and the vomiting reflex. By inhibiting the action of substance P, Befetupitant reduces the incidence and severity of nausea and vomiting associated with chemotherapy and surgery.
Related Terms
- Neurokinin 1 receptor: A type of receptor found in the nervous system that binds to the neuropeptide substance P.
- Substance P: A neuropeptide involved in pain perception and the vomiting reflex.
- Chemotherapy-induced nausea and vomiting: A common side effect of chemotherapy treatment for cancer.
- Postoperative nausea and vomiting: A common complication following surgery.
See Also
- Neurokinin 1 receptor antagonist: A class of drugs that includes Befetupitant.
- Chemotherapy: A type of cancer treatment that uses drugs to kill cancer cells.
- Surgery: A medical procedure that involves the physical alteration of body tissues.
External links
- Medical encyclopedia article on Befetupitant
- Wikipedia's article - Befetupitant
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