Neointima
Neointima
Neointima (pronunciation: nee-oh-in-ti-ma) is a term used in medicine and pathology to describe the new inner layer of cells that forms in a blood vessel following injury or disease.
Etymology
The term "neointima" is derived from the Greek words "neo," meaning new, and "intima," referring to the innermost layer of a structure.
Definition
Neointima is a pathological phenomenon that occurs when the innermost layer of the artery, known as the intima, undergoes thickening due to the proliferation of smooth muscle cells. This process is often a response to vascular injury or disease, such as atherosclerosis or following angioplasty or stent placement.
Related Terms
- Intima: The innermost layer of a blood vessel.
- Media (anatomy): The middle layer of the wall of a blood vessel.
- Atherosclerosis: A disease in which plaque builds up inside your arteries.
- Angioplasty: A procedure to restore blood flow through the artery.
- Stent: A small mesh tube that’s used to treat narrow or weak arteries.
- Smooth muscle cells: The type of cells that make up the walls of blood vessels and organs.
Clinical Significance
The formation of a neointima can lead to restenosis, or the re-narrowing of a blood vessel following treatment to widen it. This can occur after procedures such as angioplasty or stent placement. Neointima formation is a significant clinical problem, as it can lead to the recurrence of symptoms and the need for further treatment.
External links
- Medical encyclopedia article on Neointima
- Wikipedia's article - Neointima
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