Coxsackievirus-induced cardiomyopathy

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Coxsackievirus-induced cardiomyopathy
Synonyms Viral myocarditis
Pronounce N/A
Specialty N/A
Symptoms Chest pain, fatigue, shortness of breath, arrhythmia
Complications Heart failure, sudden cardiac death
Onset Sudden or gradual
Duration Variable
Types N/A
Causes Coxsackievirus infection
Risks Immunosuppression, genetic predisposition
Diagnosis Electrocardiogram, echocardiogram, cardiac MRI, endomyocardial biopsy
Differential diagnosis Ischemic heart disease, dilated cardiomyopathy, pericarditis
Prevention Hand hygiene, vaccination (experimental)
Treatment Supportive care, antiviral therapy, immunosuppressive therapy
Medication N/A
Prognosis Variable; can be self-limiting or lead to chronic heart disease
Frequency Rare
Deaths N/A


- Coxsackieviruses-induced cardiomyopathy are positive-stranded RNA viruses in picornavirus family and the genus enterovirus, acute enterovirus infections such as Coxsackievirus B3 have been identified as the cause of virally induced acute myocarditis, resulting in dilated cardiomyopathy. Dilated cardiomyopathy in humans can be caused by multiple factors including hereditary defects in the cytoskeletal protein dystrophin in Duchenne muscular dystrophy (DMD) patients). A heart that undergoes dilated cardiomyopathy shows unique enlargement of ventricles, and thinning of the ventricular wall that may lead to heart failure. In addition to the genetic defects in dystrophin or other cytoskeletal proteins, a subset of dilated cardiomyopathy is linked to enteroviral infection in the heart, especiall [[Category:Uncategorized

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