Histidinemia

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Histidinemia

Histidinemia (pronounced his-ti-di-nee-mia) is a rare metabolic disorder characterized by elevated levels of the amino acid histidine in the blood. It is an autosomal recessive disorder, meaning that an individual must inherit two copies of the defective gene, one from each parent, in order to develop the condition.

Etymology

The term "Histidinemia" is derived from the name of the amino acid "histidine" and the Greek word "haima" meaning blood. It refers to the presence of an abnormally high level of histidine in the blood.

Symptoms

Symptoms of Histidinemia can vary widely among affected individuals. They may include developmental delay, speech and language problems, and learning difficulties. Some individuals may also have ataxia, a condition characterized by a lack of muscle control or coordination of voluntary movements.

Diagnosis

Diagnosis of Histidinemia is typically made through a blood test that measures the level of histidine in the blood. Genetic testing may also be used to confirm the diagnosis and identify carriers of the disorder.

Treatment

Treatment for Histidinemia primarily involves a low-histidine diet to help reduce the level of histidine in the blood. In some cases, medication may also be prescribed to help manage symptoms.

Related Terms

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