Carglumic acid
Carglumic Acid
Carglumic acid (pronounced: kar-gloo-mik as-id) is a medication used to treat hyperammonemia, a condition characterized by high levels of ammonia in the blood. It is specifically used for hyperammonemia due to N-acetylglutamate synthase deficiency and certain other urea cycle disorders.
Etymology
The term "Carglumic acid" is derived from the chemical name Carbamoyl-glutamic acid.
Usage
Carglumic acid works by activating the enzyme carbamoyl phosphate synthetase 1 (CPS1), which helps to kickstart the urea cycle. This, in turn, aids in the removal of excess ammonia from the body.
Related Terms
- Hyperammonemia: A condition characterized by high levels of ammonia in the blood.
- N-acetylglutamate synthase: An enzyme that plays a crucial role in the urea cycle.
- Urea cycle disorders: A group of rare disorders affecting the urea cycle, a series of biochemical processes in the liver.
- Carbamoyl phosphate synthetase 1: An enzyme that plays a crucial role in the urea cycle.
Side Effects
Like all medications, carglumic acid can cause side effects. Common side effects include vomiting, abdominal pain, fever, and diarrhea. If these side effects persist or worsen, patients are advised to contact their healthcare provider immediately.
Precautions
Before starting treatment with carglumic acid, patients should inform their healthcare provider about any other medications they are taking, as well as any allergies or medical conditions they have.
External links
- Medical encyclopedia article on Carglumic acid
- Wikipedia's article - Carglumic acid
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