Imiglucerase
Imiglucerase
Imiglucerase (pronounced as im-i-gloo-ser-ase) is a medication used in the treatment of Gaucher's disease. It is a recombinant form of the human enzyme beta-glucocerebrosidase, which is deficient in individuals with Gaucher's disease.
Etymology
The term "Imiglucerase" is derived from the words "imig" (short for "imitation") and "glucerase" (short for "glucocerebrosidase enzyme"). It signifies the drug's function as a replacement for the deficient enzyme in Gaucher's disease.
Usage
Imiglucerase is used to treat the non-neurological manifestations of Gaucher's disease, a genetic disorder caused by the deficiency of the enzyme beta-glucocerebrosidase. This deficiency leads to an accumulation of certain fats in the body, causing various symptoms such as anemia, bone disease, and enlargement of the liver and spleen. By providing a replacement for the deficient enzyme, Imiglucerase helps to reduce these symptoms.
Related Terms
- Gaucher's disease: A genetic disorder caused by the deficiency of the enzyme beta-glucocerebrosidase.
- Beta-glucocerebrosidase: An enzyme that breaks down certain fats in the body. Its deficiency leads to Gaucher's disease.
- Enzyme replacement therapy: A treatment method that involves replacing a deficient enzyme with a functional one. Imiglucerase is used in enzyme replacement therapy for Gaucher's disease.
See Also
- Velaglucerase alfa: Another medication used in the treatment of Gaucher's disease.
- Taliglucerase alfa: A plant-derived recombinant form of the human enzyme beta-glucocerebrosidase.
External links
- Medical encyclopedia article on Imiglucerase
- Wikipedia's article - Imiglucerase
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