Elosulfase alfa
Elosulfase alfa
Elosulfase alfa (pronounced as eh-loh-SUL-fase AL-fa) is a medication used in the treatment of Mucopolysaccharidosis IV (MPS IV), also known as Morquio Syndrome. It is an enzyme replacement therapy that works by replacing the deficient enzyme, N-acetylgalactosamine-6-sulfatase, in patients with MPS IV.
Etymology
The name 'Elosulfase alfa' is derived from the enzyme it replaces, N-acetylgalactosamine-6-sulfatase. The 'alfa' denotes that it is a form of the enzyme produced through recombinant DNA technology.
Usage
Elosulfase alfa is used to treat patients with Mucopolysaccharidosis IV, a rare genetic disorder characterized by the body's inability to break down certain sugars and proteins. This leads to a buildup of these substances in the body, causing various health problems. By replacing the deficient enzyme, Elosulfase alfa helps to reduce the symptoms of MPS IV.
Related Terms
- Enzyme replacement therapy: A treatment method that involves replacing a missing or deficient enzyme in patients with certain genetic disorders.
- Mucopolysaccharidosis: A group of metabolic disorders caused by the absence or malfunctioning of certain enzymes needed to break down molecules called glycosaminoglycans.
- Morquio Syndrome: Another name for Mucopolysaccharidosis IV, named after the doctor who first described the condition.
- N-acetylgalactosamine-6-sulfatase: The enzyme that is deficient in patients with Mucopolysaccharidosis IV.
External links
- Medical encyclopedia article on Elosulfase alfa
- Wikipedia's article - Elosulfase alfa
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