Ivacaftor

Ivacaftor (pronounced as eye-va-KAF-tor) is a medication used for the treatment of Cystic Fibrosis in individuals with certain mutations in the CFTR gene.

Etymology

The name Ivacaftor is derived from its chemical structure. The "iva" part of the name is from the chemical name, while "caftor" is a common suffix for drugs that affect the CFTR protein.

Usage

Ivacaftor is used to treat cystic fibrosis in patients who have one of several specific mutations in the CFTR gene that are responsive to this drug. These mutations cause the CFTR protein to be made in insufficient amounts or to function improperly. Ivacaftor helps to increase the amount of CFTR protein that the body makes and/or helps the CFTR protein function better.

Related Terms

• Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
• Cystic Fibrosis
• Mutation
• Protein
• Gene

See Also

• Lumacaftor
• Tezacaftor

References

• National Center for Biotechnology Information. "PubChem Compound Summary for CID 11523173, Ivacaftor" PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Ivacaftor. Accessed 20 November, 2021.
• "Ivacaftor: MedlinePlus Drug Information." MedlinePlus, U.S. National Library of Medicine, 16 July 2021, https://medlineplus.gov/druginfo/meds/a613014.html.

External links

• Medical encyclopedia article on Ivacaftor
• Wikipedia's article - Ivacaftor

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