Template:Chromalveolate antiparasitics

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Antiparasitics – antiprotozoal agents – Chromalveolata antiparasitics (P01)

Conoidasida/
(Coccidiostats)

Cryptosporidiosis	* thiazolides (nitazoxanide)
Isosporiasis	* trimethoprim/sulfamethoxazole^#
Toxoplasmosis	* pyrimethamine sulfadiazine clindamycin atovaquone

Individual
agents

Hemozoin
inhibitors

Aminoquinolines	* (4-): amodiaquine^# chloroquine^# hydroxychloroquine^# (8-): primaquine^# pamaquine^‡ tafenoquine
4-Methanolquinolines	* mefloquine^# quinine^# quinidine
Other	* lumefantrine + artemether^# halofantrine

DHFR inhibitors	* pyrimethamine cycloguanil biguanides chlorproguanil proguanil^#
Sulfonamides	* sulfadoxine sulfalene
Co-formulation	* sulfadoxine/pyrimethamine (SP)^#

Sesquiterpene
lactones

Other

* atovaquone (+ proguanil)

Combi-
nations

Fixed-dose (co-formulated) ACTs	* artemether/lumefantrine^# arterolane/piperaquine artesunate/amodiaquine (ASAQ) artesunate/mefloquine (ASMQ) artesunate/pyronaridine piperaquine/dihydroartemisinin
Other combinations (not co-formulated)	* artesunate/mefloquine artesunate/SP quinine/clindamycin quinine/doxycycline quinine/tetracycline

* Balantidiasis: tetracycline

* Blastocystosis: metronidazole

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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