Periventricular leukomalacia: Difference between revisions
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{{short description|Degeneration of white matter near the lateral ventricles of the brain}} | |||
[[File:Gray734.png|Drawing of the lateral and third ventricles of the brain. Periventricular leukomalacia involves death of the white matter surrounding the lateral ventricles in fetuses and infants. (Image from ''Gray's Anatomy'', 1918 edition|thumb]] | |||
'''Periventricular leukomalacia''' ('''PVL''') is a form of [[white matter]] brain injury, characterized by the softening of the white matter near the ventricles. These ventricles are filled with fluid and are located in the center of the brain. The condition often affects premature infants, leading to long-term developmental delays and motor disorders. | '''Periventricular leukomalacia''' ('''PVL''') is a form of [[white matter]] brain injury, characterized by the softening of the white matter near the ventricles. These ventricles are filled with fluid and are located in the center of the brain. The condition often affects premature infants, leading to long-term developmental delays and motor disorders. | ||
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* [[White matter]] | * [[White matter]] | ||
== External links == | |||
{{Medical resources | |||
| DiseasesDB = 9868 | |||
| ICD10 = {{ICD10|P|91|2|p|90}} | |||
| ICD9 = {{ICD9|779.7}} | |||
| ICDO = | |||
| OMIM = | |||
| MedlinePlus = 007232 | |||
| eMedicineSubj = ped | |||
| eMedicineTopic = 1773 | |||
| MeshID = D007969 | |||
}} | |||
{{Certain conditions originating in the perinatal period}} | |||
{{DEFAULTSORT:Periventricular Leukomalacia}} | |||
[[Category:Central nervous system disorders]] | |||
[[Category:Neonatology]] | |||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
Revision as of 15:52, 12 January 2025
Degeneration of white matter near the lateral ventricles of the brain
Periventricular leukomalacia (PVL) is a form of white matter brain injury, characterized by the softening of the white matter near the ventricles. These ventricles are filled with fluid and are located in the center of the brain. The condition often affects premature infants, leading to long-term developmental delays and motor disorders.
Causes
The exact cause of PVL is unknown, but it is believed to be due to a lack of oxygen or blood flow to the periventricular area of the brain, which results in the death of brain tissue. This lack of oxygen or blood flow can occur before, during, or after birth. Factors that may contribute to the development of PVL include infection, inflammation, and premature birth.
Symptoms
The symptoms of PVL vary depending on the severity of the injury and the specific areas of the brain that are affected. Common symptoms include motor disorders, developmental delays, and cognitive impairments. In severe cases, children with PVL may have cerebral palsy, epilepsy, or learning disabilities.
Diagnosis
PVL is typically diagnosed through magnetic resonance imaging (MRI) or ultrasound of the brain. These imaging tests can reveal the characteristic softening and cystic degeneration of the white matter near the ventricles.
Treatment
There is currently no cure for PVL. Treatment is focused on managing symptoms and promoting the child's development and quality of life. This may include physical therapy, occupational therapy, speech therapy, and special education services.
Prognosis
The prognosis for children with PVL depends on the severity of the injury and the specific areas of the brain that are affected. Some children may have mild symptoms and relatively normal development, while others may have severe disabilities.
See also
External links
| Conditions originating in the perinatal period / fetal disease | ||||||||||
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