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Template
:
Coagulation
From WikiMD's WELLNESSPEDIA
Proteins
involved in
coagulation
Coagulation factors
Primary hemostasis
*
vWF
platelet membrane glycoproteins
:
Ib
(
A
B
IX
)
IIb/IIIa
(
IIb
IIIa
)
VI
Intrinsic pathway
*
HMWK
/
Bradykinin
Prekallikrein
/
Kallikrein
XII "Hageman"
XI
IX
VIII
Extrinsic pathway
*
III "Tissue factor"
VII
Common pathway
*
X
V
II "(Pro)thrombin"
I "Fibrin"
Fibrinogen
(
FGA
,
FGG
)
XIII
Coagulation inhibitors
*
Antithrombin (inhibits II, IX, X, XI, XII)
Protein C (inhibits V, VIII)
/
Protein S (cofactor for protein C)
Protein Z (inhibits X)
ZPI (inhibits X, XI)
TFPI (inhibits III)
Thrombolysis
/
fibrinolysis
*
Plasmin
tPA
/
urokinase
PAI-1
/
2
α2-AP
α2-macroglobulin
TAFI
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