Kallikrein

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Kallikrein

Kallikrein (pronunciation: kal-uh-kreen) is a group of enzymes known for their proteolytic properties.

Etymology

The term "kallikrein" is derived from the Greek word "kallikreas," which translates to "pancreas." This is because the first kallikrein enzyme was discovered in the pancreas.

Definition

Kallikreins are a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. They are involved in a variety of biological processes, including blood clotting, inflammation, and blood pressure regulation.

Function

Kallikreins play a crucial role in the regulation of blood pressure. They do this by producing bradykinin, a peptide that causes blood vessels to dilate. In addition, kallikreins are involved in the process of inflammation, where they act to increase vascular permeability and promote the migration of leukocytes.

Related Terms

  • Serine protease: A type of enzyme that cleaves peptide bonds in proteins.
  • Bradykinin: A peptide that causes blood vessels to dilate.
  • Leukocytes: White blood cells that are involved in protecting the body against both infectious disease and foreign invaders.

See Also

External links

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