Pasireotide

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Pasireotide

Pasireotide (/pæsɪˈriːoʊtaɪd/) is a synthetic cyclic peptide and a derivative of somatostatin, a hormone that inhibits the release of several other hormones. It is primarily used in the treatment of Cushing's disease and certain types of pituitary gland tumors.

Etymology

The name "Pasireotide" is derived from the Greek words "passi", meaning "all", and "reo", meaning "flow". This refers to the drug's ability to inhibit the flow of several hormones.

Usage

Pasireotide is used to treat Cushing's disease when surgery is not an option or has not been successful. It is also used to treat certain types of pituitary gland tumors that cannot be treated with surgery or radiation.

Mechanism of Action

Pasireotide works by binding to somatostatin receptors on the surface of certain cells in the body. This binding inhibits the release of several hormones, including cortisol, which is often produced in excess in people with Cushing's disease.

Side Effects

Common side effects of Pasireotide include nausea, diarrhea, and abdominal pain. More serious side effects can include high blood sugar, gallstones, and changes in heart rhythm.

Related Terms

External links

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