Abacavir/lamivudine
Abacavir/Lamivudine
Abacavir/Lamivudine (pronunciation: a-bak-a-vir/la-miv-oo-deen) is a combination antiretroviral medication used in the treatment and prevention of HIV/AIDS.
Etymology
The name Abacavir is derived from the chemical structure of the drug, which is a carbocyclic synthetic nucleoside analogue. Lamivudine is named after its chemical structure, which is a cytidine analogue.
Usage
Abacavir/Lamivudine is used in combination with other antiretroviral agents for the treatment of HIV-1 infection. It is also used as post-exposure prophylaxis, in combination with other antiretroviral drugs, following potential HIV exposure.
Mechanism of Action
Abacavir and lamivudine are both nucleoside reverse transcriptase inhibitors (NRTIs). They work by blocking the action of reverse transcriptase, an enzyme that the HIV virus needs to replicate itself.
Side Effects
Common side effects of Abacavir/Lamivudine include nausea, vomiting, diarrhea, and fatigue. Serious side effects may include hypersensitivity reactions, lactic acidosis, and liver problems.
Related Terms
- Antiretroviral therapy
- HIV/AIDS
- Nucleoside reverse transcriptase inhibitors (NRTIs)
- Post-exposure prophylaxis
- Reverse transcriptase
See Also
External links
- Medical encyclopedia article on Abacavir/lamivudine
- Wikipedia's article - Abacavir/lamivudine
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