Fostemsavir
Fostemsavir
Fostemsavir (pronounced fos-tem-sa-vir) is an antiretroviral medication used in the treatment of HIV infections. It is a prodrug of temsavir, which inhibits the attachment of the virus to the host cell.
Etymology
The name "Fostemsavir" is derived from its status as a prodrug of temsavir. The prefix "fos-" is often used in pharmaceutical nomenclature to denote a prodrug that is activated by phosphate cleavage.
Mechanism of Action
Fostemsavir works by binding to the gp120 protein on the surface of the HIV virus, preventing the virus from attaching to and entering the host's CD4 cells. This stops the virus from replicating and reduces the amount of virus in the body.
Usage
Fostemsavir is used in combination with other antiretroviral medications to treat adults with multidrug-resistant HIV-1 infection who have failed other treatment options. It is taken orally, usually twice a day.
Side Effects
Common side effects of Fostemsavir include nausea, diarrhea, and headache. Serious side effects can include liver problems and changes in the immune system (immune reconstitution syndrome).
Related Terms
External links
- Medical encyclopedia article on Fostemsavir
- Wikipedia's article - Fostemsavir
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