CCR5
CCR5
CCR5 (pronounced "C-C-R-five") is a protein on the surface of white blood cells that is involved in the immune system as it functions as a receptor for chemokines. This protein is also utilized by HIV to enter and infect host cells.
Etymology
The term CCR5 is an abbreviation for C-C chemokine receptor type 5. The "C-C" refers to the two adjacent cysteines (amino acids) in the protein's structure, while "chemokine receptor" refers to the protein's function as a receptor for chemokines, a type of signaling molecule that attracts immune cells to sites of inflammation.
Function
CCR5 is a receptor on the surface of some types of white blood cells. The protein is involved in the immune response by acting as a receptor for chemokines, which are signaling molecules that attract immune cells to sites of inflammation. In addition to its role in the immune system, CCR5 is also used by HIV to enter and infect host cells.
Related Terms
- Chemokine: A type of signaling molecule that attracts immune cells to sites of inflammation.
- White blood cells: Cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
- HIV: A virus that attacks the immune system, and which uses CCR5 to enter and infect host cells.
- Inflammation: A part of the body's immune response where white blood cells and substances they produce protect us from infection with foreign organisms, such as bacteria and viruses.
External links
- Medical encyclopedia article on CCR5
- Wikipedia's article - CCR5
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