Florid cutaneous papillomatosis

Florid cutaneous papillomatosis is a rare paraneoplastic syndrome characterized by the sudden onset of numerous papillomas. It is often associated with internal malignancies, particularly gastric adenocarcinoma.

Clinical Presentation

Patients with florid cutaneous papillomatosis present with a sudden eruption of multiple papillomas. These are typically found on the trunk and extremities, but can also occur on the face and neck. The papillomas are usually asymptomatic, but can cause discomfort or cosmetic concern.

Associated Conditions

Florid cutaneous papillomatosis is often associated with internal malignancies. The most common associated malignancy is gastric adenocarcinoma, but it has also been reported in association with other malignancies such as lung cancer, breast cancer, and colorectal cancer.

Diagnosis

The diagnosis of florid cutaneous papillomatosis is made based on the clinical presentation and the presence of an associated malignancy. Skin biopsy may be performed to confirm the diagnosis.

Treatment

Treatment of florid cutaneous papillomatosis involves treating the underlying malignancy. The skin lesions often regress with successful treatment of the malignancy.

Prognosis

The prognosis of florid cutaneous papillomatosis is dependent on the prognosis of the associated malignancy. With successful treatment of the malignancy, the skin lesions often regress.

See Also

• Paraneoplastic syndromes
• Gastric adenocarcinoma
• Papilloma

External links

• Florid cutaneous papillomatosis at the New Zealand Dermatological Society
• Florid cutaneous papillomatosis at eMedicine

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