Dennie–Morgan fold

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Dennie–Morgan fold
Synonyms	Dennie–Morgan lines, infraorbital fold
Pronounce	N/A
Specialty	N/A
Symptoms	Prominent skin folds under the lower eyelids
Complications	N/A
Onset	N/A
Duration	N/A
Types	N/A
Causes	Often associated with atopic dermatitis
Risks	N/A
Diagnosis	Clinical examination
Differential diagnosis	Allergic shiner, periorbital edema
Prevention	N/A
Treatment	Addressing underlying atopic dermatitis
Medication	N/A
Prognosis	N/A
Frequency	Common in individuals with atopic dermatitis
Deaths	N/A

A feature of atopic dermatitis

The Dennie–Morgan fold, also known as the "Dennie–Morgan line" or "infraorbital fold," is a distinctive dermatological feature often associated with atopic dermatitis. It appears as an extra fold or line of skin under the lower eyelids.

Clinical significance

The presence of the Dennie–Morgan fold is considered a minor diagnostic criterion for atopic dermatitis, a chronic inflammatory skin condition characterized by itchy, red, and swollen skin. This fold is more commonly observed in children with atopic dermatitis, although it can also be seen in adults.

Pathophysiology

The exact cause of the Dennie–Morgan fold is not fully understood, but it is believed to be related to chronic inflammation and edema associated with atopic dermatitis. The fold may result from repeated rubbing or scratching of the skin around the eyes, which is common in individuals with this condition.

Diagnosis

The Dennie–Morgan fold is typically identified during a physical examination by a healthcare professional. It is one of several clinical features that may be used to support the diagnosis of atopic dermatitis, alongside other signs such as xerosis (dry skin), lichenification (thickened skin), and a history of allergic rhinitis or asthma.

Management

While the Dennie–Morgan fold itself does not require specific treatment, managing the underlying atopic dermatitis can help reduce its prominence. Treatment strategies may include the use of emollients, topical corticosteroids, and immunomodulators. Avoiding known triggers and maintaining good skin care practices are also important in managing atopic dermatitis.

See also

• Atopic dermatitis
• Allergic rhinitis
• Asthma
• Xerosis
• Lichenification