Necrolytic migratory erythema

Necrolytic Migratory Erythema (pronunciation: nek-roh-lit-ik my-gruh-tor-ee er-uh-thee-muh) is a rare skin condition often associated with Glucagonoma, a type of Pancreatic tumor.

Etymology

The term "Necrolytic Migratory Erythema" is derived from the Greek words "nekros" (dead), "lysis" (loosening), "migratory" (moving from place to place), and "erythema" (redness of the skin or mucous membranes).

Definition

Necrolytic Migratory Erythema is characterized by the cyclic appearance of red, blistering and peeling skin lesions that migrate across the body. The lesions are typically concentrated in the lower abdomen, buttocks, perineum, and lower extremities.

Symptoms

The primary symptom of Necrolytic Migratory Erythema is the presence of skin lesions. These lesions often begin as small, red patches that gradually enlarge and develop into blisters. As the blisters heal, they leave behind areas of darkened skin. Other symptoms may include weight loss, diabetes, deep vein thrombosis, and anemia.

Causes

Necrolytic Migratory Erythema is most commonly associated with a glucagonoma, a rare type of pancreatic tumor that produces excessive amounts of the hormone Glucagon. This hormone plays a key role in maintaining blood sugar levels and when produced in excess, can lead to a variety of symptoms, including the skin lesions characteristic of Necrolytic Migratory Erythema.

Treatment

Treatment for Necrolytic Migratory Erythema primarily involves addressing the underlying glucagonoma. This may involve surgery to remove the tumor, as well as medications to manage symptoms. In some cases, dietary changes may also be recommended to help manage symptoms.

Related Terms

• Glucagonoma
• Pancreatic tumor
• Glucagon
• Skin lesion
• Deep vein thrombosis
• Anemia

External links

• Medical encyclopedia article on Necrolytic migratory erythema
• Wikipedia's article - Necrolytic migratory erythema

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