Anasarca

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Anasarca
Synonyms	Generalized edema, massive edema
Pronounce	N/A
Specialty	N/A
Symptoms	Swelling of the entire body
Complications	Heart failure, kidney failure, liver failure
Onset	Gradual
Duration	Variable, depending on underlying cause
Types	N/A
Causes	Congestive heart failure, nephrotic syndrome, liver cirrhosis, malnutrition, capillary leak syndrome
Risks	Severe hypoalbuminemia, heart disease, kidney disease, liver disease
Diagnosis	Clinical evaluation, blood tests, urinalysis, imaging studies
Differential diagnosis	Localized edema, lymphedema, myxedema
Prevention	N/A
Treatment	Address underlying cause, diuretics, albumin infusion
Medication	N/A
Prognosis	Depends on underlying cause and response to treatment
Frequency	Common in patients with severe organ failure
Deaths	N/A

Anasarca

An individual exhibiting signs of anasarca, characterized by widespread swelling.

Anasarca refers to a medical condition that manifests as generalized edema, or widespread swelling in the body due to the accumulation of fluid in the body's tissues. This severe fluid retention is most commonly linked with conditions such as congestive heart failure, liver failure, renal failure, and severe malnutrition. Understanding the underlying causes of anasarca is essential for effective treatment and management.

Anasarca is not a disease itself but rather a symptom or result of a range of health issues, often associated with the failure of major organs or body systems.

Symptoms

Individuals with anasarca might experience:

• Swelling of the skin and appendages
• Abdominal distension
• Shortness of breath
• Limited mobility
• Discomfort or pain

Causes and Associated Conditions

1. 1. 1. Congestive Heart Failure ###

When the heart doesn't pump blood effectively, fluid can back up into the lungs, abdomen, and extremities, leading to generalized edema.

1. 1. 1. Liver Failure ###

A failing liver cannot produce enough proteins, such as albumin, leading to an imbalance of fluids in tissues.

1. 1. 1. Renal Failure ###

Diagram showing a kidney with renal failure.

Kidneys that don't function properly may cause fluid retention in the body's tissues, resulting in swelling.

1. 1. 1. Severe Malnutrition ###

Severe malnutrition, particularly protein deficiency, can result in anasarca due to the imbalance of fluids in the body's tissues.

Diagnosis

Diagnosing anasarca involves:

• Physical examination
• Reviewing medical history
• Blood tests
• Imaging studies, such as ultrasounds or MRIs
• Evaluating organ function

Treatment

Treatment of anasarca focuses on addressing the underlying cause and might include:

• Medications like diuretics to reduce fluid retention
• Dietary changes, such as reducing salt intake
• Therapies to manage heart, liver, or kidney failure
• Nutritional support for cases due to malnutrition

Prognosis

The prognosis for anasarca varies greatly and is heavily dependent on the underlying condition. Early diagnosis and appropriate treatment are crucial for improving outcomes.

Prevention

While not all causes are preventable, lifestyle choices can impact the likelihood of developing conditions leading to anasarca. These include:

• Maintaining a healthy diet
• Regular physical activity
• Avoiding alcohol abuse
• Monitoring and managing health conditions

See Also

• Edema
• Heart Failure
• Chronic Kidney Disease
• Liver Disease
• Malnutrition

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