Galactooligosaccharide: Difference between revisions

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'''Galactooligosaccharides''' (GOS), also known as '''oligogalactose''', are a type of carbohydrate that are composed of short chains of galactose molecules. They are commonly used as a prebiotic dietary supplement and are found in a variety of foods, including legumes, whole grains, and certain fruits and vegetables.
== Galactooligosaccharide ==


== Overview ==
[[File:Galactooligosaccharide.svg|thumb|right|Chemical structure of a galactooligosaccharide]]


[[Galactooligosaccharides]] are non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, thus improving host health. They are produced from lactose, which is derived from cow's milk, through the enzymatic activity of β-galactosidase.
'''Galactooligosaccharides''' (GOS) are a type of [[oligosaccharide]] that are composed of [[galactose]] units. They are commonly found in various [[dairy products]] and are known for their [[prebiotic]] properties, which means they promote the growth of beneficial [[gut microbiota]].


== Health Benefits ==
== Structure and Composition ==
 
Galactooligosaccharides consist of a chain of galactose molecules linked together by glycosidic bonds. The degree of polymerization typically ranges from two to eight galactose units. The structure of GOS can vary, but they generally have a terminal glucose unit.
 
== Sources ==


GOS have been shown to have a number of health benefits, including promoting the growth of beneficial gut bacteria, improving mineral absorption, and enhancing the body's immune response. They may also help to reduce the risk of certain diseases, such as colon cancer and inflammatory bowel disease.
GOS are naturally present in human [[breast milk]], which is one of the reasons why breastfeeding is beneficial for infant gut health. They can also be synthesized from [[lactose]] using enzymatic processes involving [[_-galactosidase]].


=== Gut Health ===
== Health Benefits ==


[[Galactooligosaccharides]] are a type of prebiotic, which means they feed the beneficial bacteria in the gut. This can help to improve gut health and digestion, and may also have benefits for the immune system.
Galactooligosaccharides are known for their ability to stimulate the growth of [[bifidobacteria]] and [[lactobacilli]] in the gut. These beneficial bacteria help in maintaining a healthy digestive system, improving [[immune function]], and potentially reducing the risk of certain [[gastrointestinal disorders]].


=== Mineral Absorption ===
== Applications ==


GOS have been shown to improve the absorption of minerals in the gut, including calcium and magnesium. This can help to support bone health and may also have benefits for cardiovascular health.
GOS are used as functional ingredients in various [[food products]], including [[infant formula]], [[yogurt]], and [[dietary supplements]]. They are valued for their ability to enhance the nutritional profile of these products by promoting gut health.


=== Immune Function ===
== Mechanism of Action ==


Research has shown that GOS can help to enhance the body's immune response, potentially helping to protect against infection and disease.
The prebiotic effect of GOS is primarily due to their resistance to digestion in the upper gastrointestinal tract. They reach the colon intact, where they are fermented by the gut microbiota, leading to the production of short-chain fatty acids and gases. This fermentation process supports the growth of beneficial bacteria.


== Safety and Side Effects ==
== Safety and Tolerability ==


GOS are generally considered safe for consumption, although they can cause side effects in some people, including bloating, gas, and diarrhea. These side effects are usually mild and go away on their own with continued use.
Galactooligosaccharides are generally recognized as safe (GRAS) for consumption. However, excessive intake may lead to gastrointestinal discomfort, such as bloating and flatulence, due to their fermentation in the colon.


== See Also ==
== Related Pages ==


* [[Prebiotics]]
* [[Prebiotic (nutrition)]]
* [[Probiotics]]
* [[Probiotic]]
* [[Gut Health]]
* [[Dietary fiber]]
* [[Digestive Health]]
* [[Human microbiome]]


[[Category:Health]]
{{Nutrition}}
[[Category:Nutrition]]
{{Carbohydrates}}
[[Category:Dietary Supplements]]


{{stub}}
[[Category:Oligosaccharides]]
[[Category:Prebiotics]]

Latest revision as of 16:26, 16 February 2025

Galactooligosaccharide[edit]

File:Galactooligosaccharide.svg
Chemical structure of a galactooligosaccharide

Galactooligosaccharides (GOS) are a type of oligosaccharide that are composed of galactose units. They are commonly found in various dairy products and are known for their prebiotic properties, which means they promote the growth of beneficial gut microbiota.

Structure and Composition[edit]

Galactooligosaccharides consist of a chain of galactose molecules linked together by glycosidic bonds. The degree of polymerization typically ranges from two to eight galactose units. The structure of GOS can vary, but they generally have a terminal glucose unit.

Sources[edit]

GOS are naturally present in human breast milk, which is one of the reasons why breastfeeding is beneficial for infant gut health. They can also be synthesized from lactose using enzymatic processes involving _-galactosidase.

Health Benefits[edit]

Galactooligosaccharides are known for their ability to stimulate the growth of bifidobacteria and lactobacilli in the gut. These beneficial bacteria help in maintaining a healthy digestive system, improving immune function, and potentially reducing the risk of certain gastrointestinal disorders.

Applications[edit]

GOS are used as functional ingredients in various food products, including infant formula, yogurt, and dietary supplements. They are valued for their ability to enhance the nutritional profile of these products by promoting gut health.

Mechanism of Action[edit]

The prebiotic effect of GOS is primarily due to their resistance to digestion in the upper gastrointestinal tract. They reach the colon intact, where they are fermented by the gut microbiota, leading to the production of short-chain fatty acids and gases. This fermentation process supports the growth of beneficial bacteria.

Safety and Tolerability[edit]

Galactooligosaccharides are generally recognized as safe (GRAS) for consumption. However, excessive intake may lead to gastrointestinal discomfort, such as bloating and flatulence, due to their fermentation in the colon.

Related Pages[edit]

Nutrition information of Galactooligosaccharide[edit]