Lysogenic cycle
Lysogenic Cycle
The Lysogenic cycle is a method of viral reproduction that involves the incorporation of the viral genome into the host cell's genome. This process is in contrast to the lytic cycle, which involves the replication of the virus and destruction of the host cell.
Overview
In the lysogenic cycle, the virus, or bacteriophage, injects its genetic material into the host cell. This genetic material, which can be either DNA or RNA, is then incorporated into the host cell's genome. This allows the virus to reproduce without killing the host cell. The virus remains dormant within the host cell, a state known as lysogeny.
Process
The lysogenic cycle begins when the bacteriophage attaches to the surface of the host cell. The bacteriophage then injects its genetic material into the host cell. This genetic material is then incorporated into the host cell's genome through a process known as recombination.
Once the viral genetic material has been incorporated into the host cell's genome, the cell continues to live and reproduce normally. The viral genetic material is replicated along with the host cell's DNA each time the cell divides.
The virus remains dormant within the host cell until it is triggered by some sort of environmental stressor. At this point, the virus enters the lytic cycle, where it begins to replicate and eventually causes the host cell to burst, releasing new viruses.
Implications
The lysogenic cycle has important implications for genetic engineering, as it allows for the insertion of new genetic material into a host cell. This can be used to modify the genetic makeup of the cell, potentially leading to new treatments for genetic diseases.
The lysogenic cycle also has implications for the study of evolution, as it provides a mechanism for horizontal gene transfer, which can contribute to genetic diversity and evolution.
See also
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Contributors: Prab R. Tumpati, MD