Thrombotic microangiopathy
Thrombotic Microangiopathy (Throm-botic Micro-angi-opathy) is a pathological condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ damage by thrombosis in capillaries and arterioles.
Etymology
The term "Thrombotic Microangiopathy" is derived from three Greek words: "Thrombos" meaning clot, "Micros" meaning small, and "Angion" meaning vessel. The term "Pathy" is derived from the Greek word "Pathos" meaning disease.
Definition
Thrombotic Microangiopathy is a broad term that encompasses various disorders, including Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS), which are characterized by the presence of small blood clots that can block blood vessels and cause damage to organs such as the kidney and brain.
Symptoms
The symptoms of Thrombotic Microangiopathy can vary depending on the specific disorder and the organs involved. Common symptoms include fatigue, fever, purpura, neurological changes, and renal impairment.
Diagnosis
Diagnosis of Thrombotic Microangiopathy typically involves blood tests to check for anemia and low platelet count, as well as tests to assess kidney function. In some cases, a biopsy of the affected organ may be necessary.
Treatment
Treatment for Thrombotic Microangiopathy depends on the underlying cause and may include plasma exchange, immunosuppressive drugs, and supportive care.
See Also
- Thrombosis
- Microangiopathy
- Hemolytic Anemia
- Thrombocytopenia
- Thrombotic Thrombocytopenic Purpura
- Hemolytic Uremic Syndrome
External links
- Medical encyclopedia article on Thrombotic microangiopathy
- Wikipedia's article - Thrombotic microangiopathy
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