Endospores
Endospores
Endospores (pronunciation: /ˈɛndoʊˌspɔːr/) are a type of dormant, tough, and non-reproductive structure produced by certain bacteria from the phylum Firmicutes. The term "endospore" is derived from the Greek words "endo," meaning within, and "spora," meaning seed.
Formation
Endospores are formed through a complex developmental process called Sporulation. When exposed to environmental stressors such as extreme temperature, radiation, or chemical exposure, the bacterium undergoes a series of changes to form an endospore. This process involves the replication of the bacterium's DNA, which is then enveloped by a tough, protective coating.
Germination
When conditions become favorable, endospores can revert to their active, vegetative state through a process known as germination. This involves the absorption of water and the rupture of the protective spore coating, allowing the bacterium to resume normal growth and division.
Resistance
Endospores are highly resistant to unfavorable environmental conditions. They can survive extreme heat, lack of nutrients, and even radiation. This resistance is due to the spore's low water content, its thick protective coating, and the presence of Dipicolinic acid, a compound that helps to stabilize the spore's DNA.
Medical Significance
Endospores are of significant medical importance as they are often difficult to eliminate and can cause serious infections. Certain pathogenic bacteria, such as Bacillus anthracis, the causative agent of anthrax, and Clostridium difficile, which causes severe diarrhea, produce endospores.
Related Terms
External links
- Medical encyclopedia article on Endospores
- Wikipedia's article - Endospores
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