Brodie abscess

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics

Brodie abscess
Synonyms	Subacute osteomyelitis
Pronounce	N/A
Specialty	N/A
Symptoms	Localized bone pain, swelling, tenderness
Complications	Chronic osteomyelitis, bone destruction
Onset	Gradual
Duration	Persistent if untreated
Types	N/A
Causes	Staphylococcus aureus infection
Risks	Trauma, previous infection, immunocompromised state
Diagnosis	MRI, X-ray, Bone scan
Differential diagnosis	Bone tumor, Osteoid osteoma, Ewing's sarcoma
Prevention	N/A
Treatment	Antibiotics, Surgical drainage
Medication	Antibiotics such as clindamycin, vancomycin
Prognosis	Good with treatment
Frequency	Rare
Deaths	N/A

Incidence

It that accounts for 2.5%–42% of primary bone infections.

Patient characteristics

The patients are younger than 25 years of age. They usually present with joint pain and localized swelling.

Signs and symptoms

Signs and symptoms of systemic disease are frequently absent and usually only have joint pain and swelling.

Brodie abscess - subacute staphlococcal osteomyelitis.

Cause

• Staphylococcus aureus (30%–60%)
• Pseudomonas (5%)
• Klebsiella (5%) and
• Coagulase-negative Staphylococcus (5%) are causative organisms.

Culture negative

20% of cultures are negative for these organisms.

Brodie Abscess MRI

Radiology

• Radiographically, an intramedullary area of central lucency with sclerotic margins is characteristic.

Differential diagnosis

• Differential diagnosis of Brodie abscess includes many forms of benign and malignant bone lesions including but not limited to bone cysts, osteoid osteoma, giant cell tumor, chondroblastoma and Ewing sarcoma.

Diagnosis

X-rays, CT scan, MRI, blood cultures etc.

Treatment

• A course of systemic antibiotics, surgical d√©bridement.
• Sometimes bone grafting maybe required a large cavity requires stabilization.