Calcinosis: Difference between revisions
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{{Infobox medical condition | |||
| name = Calcinosis | |||
| image = [[File:KimIlSungCalciumDeposit1970.png|left|thumb|Calcinosis]] | |||
| caption = Calcium deposits in soft tissues | |||
| field = [[Rheumatology]] | |||
| synonyms = | |||
| symptoms = [[Calcium]] deposits in [[soft tissue]] | |||
| complications = [[Pain]], [[ulceration]], [[infection]] | |||
| onset = Varies | |||
| duration = Chronic | |||
| causes = [[Hypercalcemia]], [[tissue damage]], [[connective tissue disease]] | |||
| risks = [[Scleroderma]], [[dermatomyositis]], [[lupus]] | |||
| diagnosis = [[X-ray]], [[CT scan]], [[MRI]], [[biopsy]] | |||
| differential = [[Gout]], [[pseudogout]], [[tumoral calcinosis]] | |||
| prevention = Managing underlying conditions | |||
| treatment = [[Surgery]], [[medications]] (e.g., [[bisphosphonates]], [[warfarin]]) | |||
| medication = [[Diltiazem]], [[sodium thiosulfate]] | |||
| prognosis = Variable, depends on underlying cause | |||
| frequency = Rare | |||
}} | |||
'''Calcinosis''' is the formation of [[calcium]] deposits in any [[soft tissue]]. It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure. | '''Calcinosis''' is the formation of [[calcium]] deposits in any [[soft tissue]]. It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure. | ||
[[File:Calcinosis cutis new image.jpg|alt=Calcinosis cutis|thumb|Calcinosis cutis]] | [[File:Calcinosis cutis new image.jpg|alt=Calcinosis cutis|left|thumb|Calcinosis cutis]] | ||
==Types== | ==Types== | ||
While calcinosis can be classified based on which tissue it originates in and also based on etiology. When it comes to the skin, also called calcinosis cutis, there are four types of calcinosis cutis: idiopathic, dystrophic, metastatic, and iatrogenic | While calcinosis can be classified based on which tissue it originates in and also based on etiology. When it comes to the skin, also called calcinosis cutis, there are four types of calcinosis cutis: idiopathic, dystrophic, metastatic, and iatrogenic | ||
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===Dystrophic calcification=== | ===Dystrophic calcification=== | ||
The most common type of calcinosis is [[dystrophic calcification]]. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices. | The most common type of calcinosis is [[dystrophic calcification]]. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices. | ||
[[File:Calcinosis of CREST syndrome.jpg|alt=Calcinosis cutis|thumb|Calcinosis cutis]] | [[File:Calcinosis of CREST syndrome.jpg|alt=Calcinosis cutis|left|thumb|Calcinosis cutis]] | ||
===Metastatic calcification=== | ===Metastatic calcification=== | ||
[[Metastatic calcification]] involves a systemic calcium excess imbalance, which can be caused by [[hypercalcemia]], [[kidney failure]], [[milk-alkali syndrome]], lack or excess of other minerals, or other causes. | [[Metastatic calcification]] involves a systemic calcium excess imbalance, which can be caused by [[hypercalcemia]], [[kidney failure]], [[milk-alkali syndrome]], lack or excess of other minerals, or other causes. | ||
===Tumoral calcinosis=== | ===Tumoral calcinosis=== | ||
The cause of the rare condition of [[tumoral calcinosis]] is not entirely understood. It is generally characterized by large, globular calcifications near joints. | The cause of the rare condition of [[tumoral calcinosis]] is not entirely understood. It is generally characterized by large, globular calcifications near joints. | ||
==See also== | ==See also== | ||
*[[Calcinosis cutis]] | *[[Calcinosis cutis]] | ||
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==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
== External links == | == External links == | ||
{{Medical resources | {{Medical resources | ||
Latest revision as of 21:12, 4 April 2025
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| Calcinosis | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Calcium deposits in soft tissue |
| Complications | Pain, ulceration, infection |
| Onset | Varies |
| Duration | Chronic |
| Types | N/A |
| Causes | Hypercalcemia, tissue damage, connective tissue disease |
| Risks | Scleroderma, dermatomyositis, lupus |
| Diagnosis | X-ray, CT scan, MRI, biopsy |
| Differential diagnosis | Gout, pseudogout, tumoral calcinosis |
| Prevention | Managing underlying conditions |
| Treatment | Surgery, medications (e.g., bisphosphonates, warfarin) |
| Medication | Diltiazem, sodium thiosulfate |
| Prognosis | Variable, depends on underlying cause |
| Frequency | Rare |
| Deaths | N/A |
Calcinosis is the formation of calcium deposits in any soft tissue. It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure.
Types[edit]
While calcinosis can be classified based on which tissue it originates in and also based on etiology. When it comes to the skin, also called calcinosis cutis, there are four types of calcinosis cutis: idiopathic, dystrophic, metastatic, and iatrogenic
Dystrophic calcification[edit]
The most common type of calcinosis is dystrophic calcification. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices.
Metastatic calcification[edit]
Metastatic calcification involves a systemic calcium excess imbalance, which can be caused by hypercalcemia, kidney failure, milk-alkali syndrome, lack or excess of other minerals, or other causes.
Tumoral calcinosis[edit]
The cause of the rare condition of tumoral calcinosis is not entirely understood. It is generally characterized by large, globular calcifications near joints.
See also[edit]
- Calcinosis cutis
- Dermatomyositis
- Fahr's syndrome
- Hypercalcemia
- Hyperphosphatemia
- Primrose syndrome
- Scleroderma
References[edit]
<references group="" responsive="1"></references>
External links[edit]
| Inborn error of metal metabolism (E83, 275) | ||||
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