Milk-alkali syndrome

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Milk-alkali syndrome

Milk-alkali syndrome (pronunciation: /mɪlk ˈælkaɪ ˈsɪndroʊm/) is a medical condition characterized by elevated blood calcium levels (hypercalcemia) and metabolic alkalosis due to the excessive intake of calcium and absorbable alkali. It is a potential side effect of overconsumption of certain over-the-counter antacids.

Etymology

The term "milk-alkali syndrome" was first used in the early 20th century when the condition was associated with the consumption of large amounts of milk and absorbable alkali, which were used as a treatment for peptic ulcer disease. The term "syndrome" is derived from the Greek word "syndromē," which means "concurrence."

Symptoms

Symptoms of milk-alkali syndrome may include nausea, vomiting, headache, irritability, and in severe cases, kidney failure or altered mental status. The severity of symptoms often correlates with the degree of hypercalcemia.

Diagnosis

Diagnosis of milk-alkali syndrome is typically based on the presence of hypercalcemia and metabolic alkalosis in the absence of other causes. Laboratory tests may include blood tests to measure calcium and bicarbonate levels, and kidney function tests.

Treatment

Treatment for milk-alkali syndrome primarily involves discontinuation of calcium and alkali intake, and hydration to promote calcium excretion. In severe cases, hospitalization may be required.

Related Terms

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