Cic: Difference between revisions

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{{PAGENAME}} - protein capicua homolog (1608 aa, ~164 kda) is encoded by the human cic gene. This protein is involved in transcriptional regulation.
{{Infobox medical condition
{{med-stub}}
| name = Chronic Idiopathic Constipation
{{dictionary-stub2}}
| image =
{{short-articles-ni}}
| caption =
| field = [[Gastroenterology]]
| symptoms = Infrequent bowel movements, hard stools, straining
| complications = [[Hemorrhoids]], [[Anal fissure]]
| onset =
| duration =
| causes = Unknown
| risks =
| diagnosis = Clinical evaluation, exclusion of other causes
| treatment = Dietary changes, laxatives, biofeedback
| medication = Fiber supplements, osmotic laxatives
| frequency =
}}
 
'''Chronic Idiopathic Constipation''' (CIC) is a common gastrointestinal disorder characterized by persistent difficulty in bowel movements, which cannot be attributed to any identifiable physiological or anatomical cause. It is a diagnosis of exclusion, meaning that other potential causes of constipation must be ruled out before diagnosing CIC.
 
==Epidemiology==
CIC affects a significant portion of the population, with varying prevalence rates reported globally. It is more common in women than in men and tends to increase with age. The condition can significantly impact quality of life, leading to discomfort and psychological distress.
 
==Pathophysiology==
The exact pathophysiology of CIC is not well understood. It is believed to involve a combination of factors, including:
* Altered [[gastrointestinal motility]]
* Dysfunction in the [[enteric nervous system]]
* Abnormalities in [[colonic transit time]]
* Impaired rectal evacuation
 
==Clinical Features==
Patients with CIC typically present with symptoms such as:
* Infrequent bowel movements (less than three per week)
* Hard or lumpy stools
* Excessive straining during defecation
* A sensation of incomplete evacuation
* Abdominal bloating and discomfort
 
==Diagnosis==
The diagnosis of CIC is primarily clinical, based on the patient's history and symptomatology. The [[Rome IV criteria]] are often used to aid in diagnosis. These criteria require the presence of symptoms for at least three months, with symptom onset at least six months prior to diagnosis.
 
===Exclusion of Other Causes===
Before diagnosing CIC, it is essential to exclude other potential causes of constipation, such as:
* [[Hypothyroidism]]
* [[Diabetes mellitus]]
* [[Irritable bowel syndrome]]
* [[Colorectal cancer]]
* [[Neurological disorders]]
 
==Management==
The management of CIC involves a combination of lifestyle modifications, pharmacological treatments, and, in some cases, behavioral therapies.
 
===Lifestyle Modifications===
* Increasing dietary fiber intake through fruits, vegetables, and whole grains
* Ensuring adequate hydration
* Regular physical activity
 
===Pharmacological Treatments===
* [[Fiber supplements]] such as psyllium
* [[Osmotic laxatives]] like polyethylene glycol
* [[Stimulant laxatives]] for short-term use
* [[Stool softeners]]
 
===Behavioral Therapies===
* [[Biofeedback therapy]] to improve pelvic floor function
 
==Complications==
If left untreated, CIC can lead to complications such as:
* [[Hemorrhoids]]
* [[Anal fissures]]
* [[Fecal impaction]]
 
==Prognosis==
The prognosis for patients with CIC varies. While some individuals may experience significant improvement with treatment, others may have persistent symptoms. Long-term management and follow-up are often necessary.
 
==See Also==
* [[Constipation]]
* [[Irritable bowel syndrome]]
* [[Functional gastrointestinal disorders]]
 
==External Links==
* [Link to a reputable medical website]
 
{{Gastroenterology}}
[[Category:Gastroenterology]]
[[Category:Functional gastrointestinal disorders]]
[[Category:Symptoms and signs: Digestive system and abdomen]]

Latest revision as of 17:03, 1 January 2025

Chronic Idiopathic Constipation
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Infrequent bowel movements, hard stools, straining
Complications Hemorrhoids, Anal fissure
Onset
Duration
Types N/A
Causes Unknown
Risks
Diagnosis Clinical evaluation, exclusion of other causes
Differential diagnosis N/A
Prevention N/A
Treatment Dietary changes, laxatives, biofeedback
Medication Fiber supplements, osmotic laxatives
Prognosis N/A
Frequency
Deaths N/A


Chronic Idiopathic Constipation (CIC) is a common gastrointestinal disorder characterized by persistent difficulty in bowel movements, which cannot be attributed to any identifiable physiological or anatomical cause. It is a diagnosis of exclusion, meaning that other potential causes of constipation must be ruled out before diagnosing CIC.

Epidemiology[edit]

CIC affects a significant portion of the population, with varying prevalence rates reported globally. It is more common in women than in men and tends to increase with age. The condition can significantly impact quality of life, leading to discomfort and psychological distress.

Pathophysiology[edit]

The exact pathophysiology of CIC is not well understood. It is believed to involve a combination of factors, including:

Clinical Features[edit]

Patients with CIC typically present with symptoms such as:

  • Infrequent bowel movements (less than three per week)
  • Hard or lumpy stools
  • Excessive straining during defecation
  • A sensation of incomplete evacuation
  • Abdominal bloating and discomfort

Diagnosis[edit]

The diagnosis of CIC is primarily clinical, based on the patient's history and symptomatology. The Rome IV criteria are often used to aid in diagnosis. These criteria require the presence of symptoms for at least three months, with symptom onset at least six months prior to diagnosis.

Exclusion of Other Causes[edit]

Before diagnosing CIC, it is essential to exclude other potential causes of constipation, such as:

Management[edit]

The management of CIC involves a combination of lifestyle modifications, pharmacological treatments, and, in some cases, behavioral therapies.

Lifestyle Modifications[edit]

  • Increasing dietary fiber intake through fruits, vegetables, and whole grains
  • Ensuring adequate hydration
  • Regular physical activity

Pharmacological Treatments[edit]

Behavioral Therapies[edit]

Complications[edit]

If left untreated, CIC can lead to complications such as:

Prognosis[edit]

The prognosis for patients with CIC varies. While some individuals may experience significant improvement with treatment, others may have persistent symptoms. Long-term management and follow-up are often necessary.

See Also[edit]

External Links[edit]

  • [Link to a reputable medical website]
Health science - Medicine - Gastroenterology - edit
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Halitosis | Nausea | Vomiting | GERD | Achalasia | Esophageal cancer | Esophageal varices | Peptic ulcer | Abdominal pain | Stomach cancer | Functional dyspepsia | Gastroparesis
Diseases of the liver - pancreas - gallbladder - biliary tree
Hepatitis | Cirrhosis | NASH | PBC | PSC | Budd-Chiari | Hepatocellular carcinoma | Acute pancreatitis | Chronic pancreatitis | Pancreatic cancer | Gallstones | Cholecystitis
Diseases of the small intestine
Peptic ulcer | Intussusception | Malabsorption (e.g. Coeliac, lactose intolerance, fructose malabsorptionWhipple's) | Lymphoma
Diseases of the colon
Diarrhea | Appendicitis | Diverticulitis | Diverticulosis | IBD (Crohn'sUlcerative colitis) | IBS | Constipation | Colorectal cancer | Hirschsprung's | Pseudomembranous colitis