Spirapril
Spirapril
Spirapril (/spɪˈræprɪl/) is a type of ACE inhibitor used in the treatment of hypertension and heart failure. It is a prodrug that is converted to its active form, spiraprilat, in the body.
Etymology
The term "Spirapril" is derived from the Latin spirare, meaning "to breathe", and aprilis, meaning "open". This is likely a reference to the drug's ability to help open up the blood vessels, improving blood flow and making it easier for the heart to pump blood.
Pharmacology
Spirapril works by inhibiting the angiotensin-converting enzyme, which is involved in the production of angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows the blood vessels. By inhibiting the production of this substance, spirapril helps to relax and widen the blood vessels, reducing blood pressure and making it easier for the heart to pump blood.
Related Terms
- ACE inhibitors: A class of drugs that spirapril belongs to. They work by inhibiting the angiotensin-converting enzyme, reducing blood pressure and easing the workload on the heart.
- Hypertension: A medical condition characterized by high blood pressure. It is one of the conditions that spirapril is used to treat.
- Heart failure: A condition in which the heart is unable to pump enough blood to meet the body's needs. Spirapril is used to treat heart failure by helping to relax and widen the blood vessels, reducing the workload on the heart.
External links
- Medical encyclopedia article on Spirapril
- Wikipedia's article - Spirapril
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