Neurotensin

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Neurotensin

Neurotensin (pronounced: noor-oh-TEN-sin) is a 13 amino acid neuropeptide that is found in the central nervous system and in the gastrointestinal tract. It was first isolated in 1973 from bovine hypothalami.

Etymology

The term "neurotensin" is derived from the words "neuro", referring to the nervous system, and "tensin", indicating its tension or pressure-related functions.

Function

Neurotensin is involved in a variety of physiological processes, including the regulation of dopamine activity, pain modulation, and the regulation of body temperature. It also has a role in the regulation of gastrointestinal motility and secretion.

Related Terms

  • Neuropeptide: A peptide that is active in the nervous system.
  • Dopamine: A type of neurotransmitter, a chemical messenger that transmits signals in the brain and other areas of the body.
  • Gastrointestinal: Relating to the stomach and the intestines.

Clinical Significance

Abnormal levels of neurotensin have been associated with a number of conditions, including schizophrenia, Parkinson's disease, and certain types of cancer. It is also being studied for its potential role in the treatment of these conditions.

See Also

References

External Links

External links

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