Menadione
Menadione
Menadione (pronunciation: meh-nuh-dye-own) is a synthetic, water-soluble vitamin K analogue. It is also known as Vitamin K3.
Etymology
The term "Menadione" is derived from the chemical name 2-methyl-1,4-naphthoquinone. The name "Vitamin K3" is due to its classification as one of the vitamins in the K group, specifically the third one discovered.
Definition
Menadione is a synthetic compound that is used as a provitamin. It is converted to active vitamin K by the body. Menadione is used in the treatment of hypoprothrombinemia, a condition characterized by low levels of prothrombin, a protein necessary for blood clotting.
Usage
Menadione is used in the medical field to treat vitamin K deficiency and conditions related to poor blood clotting. It is also used in animal feed to ensure adequate intake of vitamin K.
Related Terms
- Vitamin K: A group of structurally similar, fat-soluble vitamins that are needed for the posttranslational modification of certain proteins required for blood coagulation.
- Prothrombin: A protein present in blood plasma that is converted into active thrombin during coagulation.
- Hypoprothrombinemia: A rare blood disorder in which a deficiency in immunoreactive prothrombin, produced in the liver, results in an impaired blood clotting reaction, leading to an increased physiological risk for spontaneous bleeding.
Side Effects
Excessive usage of Menadione can lead to several side effects such as jaundice, hemolytic anemia, and hyperbilirubinemia. It is also known to cause cytotoxicity in liver cells.
See Also
External links
- Medical encyclopedia article on Menadione
- Wikipedia's article - Menadione
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