Fostamatinib
Fostamatinib
Fostamatinib (pronounced fos-ta-ma-ti-nib) is a pharmaceutical drug used in the treatment of chronic immune thrombocytopenia (ITP). It is a small molecule inhibitor of spleen tyrosine kinase (Syk), a protein involved in immune cell signaling.
Etymology
The name "Fostamatinib" is derived from its chemical structure. "Fos" refers to its phosphate group, "tama" is derived from tamatinib, a similar kinase inhibitor, and "nib" is a common suffix for kinase inhibitors.
Usage
Fostamatinib is used in the treatment of chronic immune thrombocytopenia (ITP), a condition where the immune system attacks and destroys platelets in the blood, leading to a low platelet count. It works by inhibiting the spleen tyrosine kinase (Syk), a protein involved in the signaling of immune cells. This inhibition reduces the destruction of platelets, helping to increase the platelet count in the blood.
Related Terms
- Pharmaceutical drug: A chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being.
- Chronic immune thrombocytopenia (ITP): A disorder that can lead to easy or excessive bruising and bleeding due to abnormally low platelets, the cells that help blood clot.
- Small molecule inhibitor: A type of drug that can enter cells easily because they are small enough to pass through the cell membrane.
- Spleen tyrosine kinase (Syk): A protein that plays a crucial role in the immune response and is a target for certain drugs.
External links
- Medical encyclopedia article on Fostamatinib
- Wikipedia's article - Fostamatinib
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