Batroxobin

Batroxobin is a hemostatic enzyme that is derived from the venom of the Bothrops atrox snake, also known as the fer-de-lance. It is used in medicine to promote blood clotting and to treat certain blood disorders.

History

Batroxobin was first isolated from the venom of the Bothrops atrox snake in the 1930s. It was initially used in South America to treat snakebite victims, but its use has since expanded to other areas of medicine.

Medical uses

Batroxobin is used in medicine to promote blood clotting. It works by converting fibrinogen into fibrin, which is the protein that forms the framework of a blood clot. This makes it useful in treating conditions that involve excessive bleeding, such as hemophilia and von Willebrand disease.

In addition to its hemostatic properties, batroxobin has also been found to have anti-inflammatory effects. This makes it potentially useful in treating conditions that involve inflammation, such as rheumatoid arthritis and osteoarthritis.

Side effects

Like all medicines, batroxobin can cause side effects. These can include allergic reactions, nausea, vomiting, and pain at the injection site. In rare cases, it can cause serious side effects such as anaphylaxis and thrombosis.

See also

• Bothrops atrox
• Hemostasis
• Fibrinogen
• Fibrin

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Batroxobin gallery

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  Homology model of thrombin-like enzyme batroxobin