Ulinastatin
Ulinastatin
Ulinastatin (pronounced: yoo-li-na-stat-in) is a urinary trypsin inhibitor (UTI) that is derived from human urine. It is a glycoprotein that is used as a drug in some parts of the world, particularly in Asia, for the treatment of acute pancreatitis, sepsis, and acute circulatory failure.
Etymology
The term "Ulinastatin" is derived from the Latin words "urina" meaning urine and "statin" from the class of drugs known as statins, which are used to lower cholesterol levels in the blood. Despite its name, Ulinastatin does not have any statin-like properties.
Usage
Ulinastatin is used in the treatment of various conditions such as acute pancreatitis, sepsis, and acute circulatory failure. It works by inhibiting the activity of various proteolytic enzymes such as trypsin, elastase, and chymotrypsin, which can cause tissue damage when they are released into the bloodstream during inflammation.
Related Terms
- Urinary trypsin inhibitor: A type of protein that is found in the urine and can inhibit the activity of the enzyme trypsin.
- Glycoprotein: A type of protein that has sugar molecules attached to it.
- Pancreatitis: Inflammation of the pancreas.
- Sepsis: A life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
- Acute circulatory failure: A condition where the body's organs are not getting enough blood flow.
- Proteolytic enzymes: Enzymes that break down proteins into smaller peptides or amino acids.
External links
- Medical encyclopedia article on Ulinastatin
- Wikipedia's article - Ulinastatin
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