Mast cells
Mast cells
Mast cells (pronounced: /mæst sɛlz/) are a type of white blood cell in the immune system. They are involved in the body's defense against pathogens and play a crucial role in allergic reactions and inflammation.
Etymology
The term "mast cell" is derived from the German word "Mastzellen," which was first used by Paul Ehrlich in his doctoral thesis in 1878. The term "Mast" in German means "fattening," as Ehrlich noted that these cells were filled with granules.
Function
Mast cells are involved in the body's immune response. They release chemicals such as histamine and heparin that help the body fight off infections. However, when these cells are overactive, they can cause allergic reactions and inflammation.
Related Terms
- Histamine: A compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.
- Heparin: An anticoagulant (blood thinner) that prevents the formation of blood clots.
- Inflammation: A localized physical condition in which part of the body becomes reddened, swollen, hot, and often painful, especially as a reaction to injury or infection.
- Allergy: A damaging immune response by the body to a substance, especially pollen, fur, a particular food, or dust, to which it has become hypersensitive.
See Also
External links
- Medical encyclopedia article on Mast cells
- Wikipedia's article - Mast cells
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