Guanidinium chloride
| Guanidinium chloride | |
|---|---|
| Guanidinium chloride.png | |
| Structural formula of guanidinium chloride | |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| ChemSpider ID | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| Properties | |
| Chemical Formula | |
| Molar Mass | 95.53 g/mol |
| Appearance | White crystalline solid |
| Density | 1.354 g/cm3 |
| Melting Point | 182 °C |
| Boiling Point | |
| Hazards | |
| GHS Pictograms | [[File:|50px]] |
| GHS Signal Word | |
| GHS Hazard Statements | |
| NFPA 704 | [[File:|50px]] |
| References | |
Guanidinium chloride (also known as guanidine hydrochloride) is a chemical compound with the formula CH6ClN3. It is the chloride salt of guanidine.
Structure and Properties[edit]
Guanidinium chloride is a white crystalline solid that is highly soluble in water. It is composed of the guanidinium cation (C(NH2)3+) and the chloride anion (Cl-). The guanidinium ion is planar and exhibits resonance stabilization, which contributes to its stability.
Chemical Properties[edit]
Guanidinium chloride is a strong chaotropic agent, meaning it can disrupt the structure of water and proteins. It is often used in biochemistry to denature proteins by disrupting hydrogen bonds and hydrophobic interactions.
Applications[edit]
Guanidinium chloride has several important applications in the field of biochemistry and molecular biology.
Protein Denaturation[edit]
One of the primary uses of guanidinium chloride is in the denaturation of proteins. It is commonly used in protein purification protocols to unfold proteins, allowing for the removal of contaminants and the study of protein folding and stability.
RNA Isolation[edit]
Guanidinium chloride is also used in the isolation of RNA. It helps to lyse cells and inactivate RNase enzymes, which are responsible for degrading RNA. This makes it a crucial component in RNA extraction protocols.
DNA Extraction[edit]
In addition to RNA isolation, guanidinium chloride is used in DNA extraction procedures. It helps to solubilize cellular components and protect nucleic acids from degradation.
Safety and Handling[edit]
Guanidinium chloride should be handled with care, as it can be harmful if ingested or inhaled. It may cause irritation to the skin, eyes, and respiratory tract. Proper personal protective equipment (PPE) such as gloves and goggles should be worn when handling this compound.
See Also[edit]
External Links[edit]
- [Guanidinium chloride on PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Guanidinium-chloride)
- [Guanidinium chloride safety data sheet]
| Chemical compounds | ||||||
|---|---|---|---|---|---|---|
This chemical compound-related article is a stub.
|
| Biochemistry | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
This biochemistry related article is a stub.
|
Ad. Transform your life with W8MD's
GLP-1 weight loss injections special from $29.99
W8MD Medical Weight Loss, Sleep and Medspa offers physician-supervised medical weight loss programs: NYC medical weight loss Philadelphia medical weight loss
Affordable GLP-1 Weight Loss ShotsAffordable GLP-1 Weight Loss Shots
Budget GLP-1 injections NYC (insurance & self-pay options) Popular treatments:
- Semaglutide starting from $29.99/week
- Tirzepatide starting from $45.00/week
✔ Most insurances accepted for visits ✔ Prior authorization support when eligible
Start your physician weight loss NYC journey today:
📍 NYC: Brooklyn weight loss center 📍 Philadelphia: Philadelphia weight loss center
📞 Call: 718-946-5500 (NYC) | 215-676-2334 (Philadelphia)
Tags: Affordable GLP1 weight loss NYC, Wegovy NYC, Zepbound NYC, Philadelphia medical weight loss
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
