Foregut
Foregut
Foregut (/ˈfɔːrˌɡʌt/) is a term used in the field of Embryology to describe the anterior part of the alimentary canal, from the mouth to the duodenum at the entrance of the bile duct, and is developed from the embryonic gut.
Etymology
The term "Foregut" is derived from the Old English words 'fore' meaning "before" or "front" and 'gut' meaning "intestine".
Anatomy
The foregut is one of the three regions of the embryonic gut, the other two being the midgut and hindgut. It gives rise to several key structures within the digestive and respiratory systems. These include the pharynx, esophagus, stomach, liver, biliary tract, and pancreas.
Development
During the fourth week of human embryonic development, the foregut, midgut, and hindgut are established. The foregut develops into the pharynx, the esophagus, the stomach, and the proximal part of the duodenum. The respiratory tract also develops from the foregut.
Clinical Significance
Abnormalities in the development of the foregut can lead to a number of congenital conditions. These include Esophageal atresia, Tracheoesophageal fistula, and Duodenal atresia.
Related Terms
- Endoderm: The innermost layer of the cells or tissue of an embryo in early development, or the parts derived from this, which include the lining of the gut and associated structures.
- Mesoderm: The middle layer of an embryo in early development, between the endoderm and ectoderm.
- Ectoderm: The outermost layer of cells or tissue of an embryo in early development, or the parts derived from this, which include the epidermis, and nerve tissue.
External links
- Medical encyclopedia article on Foregut
- Wikipedia's article - Foregut
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