CYLD
CYLD (pronounced as "sild") is a gene that provides instructions for making a protein that helps regulate cell signaling pathways. This protein plays a crucial role in controlling cell growth and preventing the formation of tumors.
Etymology
The term "CYLD" is an abbreviation for "Cylindromatosis", a condition associated with mutations in this gene. The term "Cylindromatosis" is derived from the Greek words "kylin" (meaning cylinder) and "oma" (meaning tumor), referring to the cylindrical shape of the tumors that can form as a result of mutations in this gene.
Function
The CYLD protein acts as a tumor suppressor, which means it regulates cell division by keeping cells from growing and dividing too rapidly or in an uncontrolled way. It does this by removing chemical groups known as ubiquitins from other proteins. This process, known as deubiquitination, can affect various cellular functions, including protein degradation, cell cycle progression, and DNA repair.
Related Terms
- Cylindromatosis (CYLD Cutaneous Syndrome): A condition characterized by the growth of numerous skin tumors, caused by mutations in the CYLD gene.
- Ubiquitin: A small protein that is attached to other proteins to mark them for degradation.
- Tumor Suppressor: A type of gene that makes a protein to help regulate the cell cycle and prevent cancer.
- DNA Repair: The collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
See Also
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