Opisthorchiasis

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Opisthorchiasis
Synonyms
Pronounce N/A
Specialty Gastroenterology, Infectious disease
Symptoms Abdominal pain, diarrhea, fatigue, jaundice
Complications Cholangiocarcinoma, bile duct obstruction, liver cirrhosis
Onset
Duration
Types
Causes Opisthorchis viverrini, Opisthorchis felineus
Risks Consumption of raw or undercooked freshwater fish
Diagnosis Stool examination, serology
Differential diagnosis
Prevention Avoiding raw or undercooked fish
Treatment Praziquantel, albendazole
Medication
Prognosis
Frequency Endemic in parts of Southeast Asia and Eastern Europe
Deaths


Incidence of CCA and O. viverrini in Thailand from 1990–2001

Opisthorchiasis is a parasitic disease caused by species in the genus Opisthorchis. Chronic infection may lead to severe liver disease.

Causes[edit]

Opisthorchiasis is caused by the trematodes Opisthorchis viverrini and Opisthorchis felineus. Humans contract the disease by eating raw or undercooked fish containing the larvae of the parasite.

Symptoms[edit]

The symptoms of opisthorchiasis can range from mild to severe, and may include fever, fatigue, abdominal pain, and jaundice. In severe cases, the disease can lead to cholangitis, cholangiocarcinoma, and liver cirrhosis.

Diagnosis[edit]

Diagnosis of opisthorchiasis is typically made by identifying the eggs of the parasite in a stool sample. Other diagnostic methods may include serology and imaging studies.

Treatment[edit]

Treatment for opisthorchiasis typically involves the use of the antiparasitic drug praziquantel. In severe cases, surgical intervention may be necessary.

Prevention[edit]

Prevention of opisthorchiasis primarily involves avoiding the consumption of raw or undercooked fish in areas where the disease is endemic.

See also[edit]

References[edit]

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External links[edit]

Further reading[edit]

  • Opisthorchis viverrini and Opisthorchiasis: The Complex Relationship Between Parasite and Host by Banchob Sripa
  • Opisthorchiasis: An Overlooked Danger by Paul J. Brindley







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