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Template:Obsessive–compulsive disorder

From WikiMD's Medical Encyclopedia

Revision as of 03:31, 30 April 2024 by Prab (talk | contribs) (CSV import)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Obsessive–compulsive disorder
History
* Yale–Brown Obsessive Compulsive Scale
Biology
Neuroanatomy
* Basal ganglia (striatum)
  • Orbitofrontal cortex
  • Cingulate cortex
  • Brain-derived neurotrophic factor
Receptors
* 5-HT1Dβ
  • 5-HT2A
  • 5-HT2C
  • μ Opioid
  • H2
  • NK1
  • M4
  • NMDA
Symptoms
* Obsessions (associative
  • diagnostic
  • injurious
  • scrupulous
  • pathogenic
  • sexual)
  • Compulsions (impulses, rituals
  • tics)
  • Thought suppression (avoidance)
  • Hoarding (animals, books
  • possessions)
Spectrum
Treatment
Serotonergics
Selective serotonin reuptake inhibitors
* Escitalopram
  • Fluoxetine
  • Fluvoxamine
  • Paroxetine
  • Sertraline
  • Citalopram
  • Nefazodone
Serotonin–norepinephrine reuptake inhibitors
* Venlafaxine
  • Desvenlafaxine
  • Duloxetine
Serotonin–norepinephrine–dopamine reuptake inhibitors
* Nefazodone
Monoamine oxidase inhibitors
* Phenelzine
  • Tranylcypromine
Tricyclic antidepressants
* Clomipramine
Mu opioidergics
* Hydrocodone
  • Morphine
  • Tramadol
Anticholinergics
* Diphenhydramine
NMDA glutamatergics
* Riluzole


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