Perforating calcific elastosis

Perforating calcific elastosis is a rare skin condition characterized by the deposition of calcium in the skin's elastic fibers, leading to their perforation. It is often associated with kidney disease, particularly in patients undergoing dialysis.

Symptoms

The primary symptom of perforating calcific elastosis is the appearance of small, white, firm papules on the skin. These papules are typically found on the extremities, particularly the hands and feet. They may be asymptomatic or cause mild itching.

Causes

The exact cause of perforating calcific elastosis is unknown. However, it is often associated with chronic kidney disease and dialysis. The condition is thought to result from an imbalance in calcium and phosphate metabolism, leading to the deposition of calcium in the skin's elastic fibers.

Diagnosis

Diagnosis of perforating calcific elastosis is typically made through a skin biopsy. Under the microscope, the skin shows characteristic changes, including the presence of calcium deposits in the elastic fibers and their perforation.

Treatment

There is no specific treatment for perforating calcific elastosis. Management is primarily aimed at controlling the underlying kidney disease and maintaining a balance in calcium and phosphate levels. Topical steroids and emollients may be used to manage the skin symptoms.

See also

• Calciphylaxis
• Chronic kidney disease
• Dialysis

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References

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External links

• Perforating calcific elastosis in a patient on chronic dialysis: a case report and review of the literature
• Perforating calcific elastosis: a review of the literature

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  Histopathology of perforating calcific elastosis