Perforating calcific elastosis
Perforating calcific elastosis
Perforating calcific elastosis (pronunciation: per-fo-rating cal-cif-ic el-as-to-sis) is a rare skin disorder characterized by the deposition of calcium in the dermis and subsequent elimination of these deposits through the epidermis.
Etymology
The term "Perforating calcific elastosis" is derived from the Latin words "perforare" meaning to pierce, "calcificare" meaning to harden by calcium, and "elastosis" referring to the degeneration of elastic tissue.
Symptoms
The primary symptom of perforating calcific elastosis is the presence of small, firm, white papules on the skin. These papules are often found on the extremities, particularly the hands and feet. Other symptoms may include itching and discomfort.
Causes
Perforating calcific elastosis is caused by the accumulation of calcium in the dermis, the layer of skin beneath the epidermis. This can occur due to a variety of factors, including chronic kidney disease, hyperparathyroidism, and certain medications. The exact mechanism by which these calcium deposits are eliminated through the epidermis is not fully understood.
Diagnosis
Diagnosis of perforating calcific elastosis is typically made through a combination of clinical examination and histopathological analysis. This involves taking a small sample of skin (a biopsy) and examining it under a microscope.
Treatment
Treatment for perforating calcific elastosis primarily involves managing the underlying condition that is causing the calcium accumulation. This may involve changes to medication, dialysis for kidney disease, or surgery for hyperparathyroidism. Topical treatments may also be used to manage symptoms.
Related Terms
External links
- Medical encyclopedia article on Perforating calcific elastosis
- Wikipedia's article - Perforating calcific elastosis
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