TAS2R41

TAS2R41

TAS2R41 is a protein that in humans is encoded by the TAS2R41 gene. It is a member of the TAS2R (Taste 2 Receptor) gene family, which is responsible for the bitter taste perception.

Function

The TAS2R41 protein is a G protein-coupled receptor that is expressed in the taste receptor cells of the tongue and palate epithelia. This protein is involved in the perception of bitter taste, and it is activated by a variety of bitter-tasting compounds.

Genetics

The TAS2R41 gene is located on chromosome 12 in humans. Variations in this gene have been associated with differences in the ability to taste certain bitter compounds. People who have a certain variant of the TAS2R41 gene are more sensitive to the bitter taste of certain substances, such as phenylthiocarbamide (PTC) and propylthiouracil (PROP).

Clinical significance

Understanding the function of TAS2R41 and other taste receptors may have implications for the treatment of obesity and other eating disorders. For example, if a person has a heightened sensitivity to bitter taste, they may be less likely to consume bitter-tasting foods and beverages, which could potentially influence their dietary choices and overall health.

See also

• Taste receptor
• G protein-coupled receptor
• Phenylthiocarbamide
• Propylthiouracil

References

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