Autoinflammatory diseases

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Autoinflammatory diseases (pronunciation: /ˌɔːtoʊˌɪnfləˈmeɪtəri dɪˈziːzɪz/) are a group of medical conditions characterized by abnormal inflammation in the body that is not caused by pathogens or autoimmune diseases.

Etymology

The term "autoinflammatory" is derived from the Greek words "auto" meaning self, and "inflammatory" referring to the body's inflammatory response.

Definition

Autoinflammatory diseases are caused by genetic mutations that result in the body's immune system attacking its own cells and tissues, causing inflammation. Unlike autoimmune diseases, autoinflammatory diseases do not involve the production of autoantibodies or T-cells.

Types of Autoinflammatory Diseases

There are several types of autoinflammatory diseases, including:

Symptoms

Common symptoms of autoinflammatory diseases include recurrent fever, rash, joint pain, and abdominal pain. The severity and frequency of these symptoms can vary greatly among individuals and between different types of autoinflammatory diseases.

Diagnosis

Diagnosis of autoinflammatory diseases typically involves a combination of medical history, physical examination, and laboratory tests. Genetic testing may also be used to confirm a diagnosis in some cases.

Treatment

Treatment for autoinflammatory diseases typically involves managing symptoms and preventing complications. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and biologic therapies.

See Also

External links

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