Neonatal-onset multisystem inflammatory disease
Neonatal-onset multisystem inflammatory disease (pronounced: nee-oh-NAY-tuhl ON-set MUL-tee-sis-tem in-flam-MA-tory dis-EASE), often abbreviated as NOMID, is a rare genetic disorder that affects multiple systems of the body and is present from birth.
Etymology
The term "Neonatal-onset multisystem inflammatory disease" is derived from the Latin words 'neonatus' meaning 'newborn', 'multus' meaning 'many', 'systema' meaning 'combined', 'inflammatio' meaning 'inflammation', and 'disease' from the Old French 'desaise' meaning 'lack of ease'.
Definition
NOMID is a severe form of CAPS (Cryopyrin-Associated Periodic Syndromes), a group of autoinflammatory diseases. It is characterized by fever, skin rash, joint pain, and inflammation in various parts of the body including the nervous system and sensory organs.
Symptoms
The symptoms of NOMID are usually noticeable from birth and may include skin rash, chronic meningitis, significant hearing and vision loss, and skeletal abnormalities.
Causes
NOMID is caused by mutations in the NLRP3 gene, which is involved in the production of a protein that helps the body's immune system respond to infections and injuries.
Treatment
Treatment for NOMID often involves managing symptoms and preventing complications. This may include anti-inflammatory medications, corticosteroids, and targeted therapies such as Canakinumab and Anakinra.
Related Terms
External links
- Medical encyclopedia article on Neonatal-onset multisystem inflammatory disease
- Wikipedia's article - Neonatal-onset multisystem inflammatory disease
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski