Large granular lymphocytic leukemia

From Food & Medicine Encyclopedia


Large granular lymphocytic leukemia
Synonyms LGL leukemia
Pronounce N/A
Specialty N/A
Symptoms Fatigue, neutropenia, anemia, splenomegaly, rheumatoid arthritis
Complications Infections, autoimmune disorders
Onset Typically in adults
Duration Chronic
Types N/A
Causes Unknown, possibly autoimmune
Risks Rheumatoid arthritis, autoimmune disorders
Diagnosis Blood test, bone marrow biopsy, flow cytometry
Differential diagnosis Chronic lymphocytic leukemia, T-cell prolymphocytic leukemia, Felty's syndrome
Prevention N/A
Treatment Immunosuppressive therapy, chemotherapy, cyclosporine, methotrexate
Medication N/A
Prognosis Variable, often indolent
Frequency Rare
Deaths N/A


Large granular lymphocytic leukemia (LGL) is a type of leukemia that affects a specific type of white blood cell called lymphocytes. It is a slow-growing form of leukemia and symptoms may not appear for years. Treatment options include observation, immunosuppressive therapy, or chemotherapy.

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