Epithelioid

Epithelioid is a term used to describe cells that have been altered in such a way that they resemble epithelial cells. These cells are typically found in certain types of tumors and granulomas. The term "epithelioid" is derived from the word "epithelium", which refers to the layer of cells that lines the surfaces and cavities of the body's organs.

Characteristics of Epithelioid Cells

Epithelioid cells are characterized by their large size, abundant eosinophilic cytoplasm, and centrally located nucleus. They also have a distinct cell border and often form tight clusters or sheets. These cells are typically found in granulomas and certain types of tumors, including carcinomas and melanomas.

Epithelioid Tumors

Epithelioid tumors are a type of neoplasm that is composed predominantly of epithelioid cells. These tumors can occur in various parts of the body, including the skin, lungs, and gastrointestinal tract. Some common types of epithelioid tumors include epithelioid sarcoma, epithelioid hemangioendothelioma, and epithelioid angiosarcoma.

Epithelioid Granulomas

Epithelioid granulomas are a type of granuloma that is composed predominantly of epithelioid cells. These granulomas are typically associated with certain types of inflammatory diseases, including sarcoidosis and tuberculosis.

Diagnosis and Treatment

The diagnosis of conditions involving epithelioid cells typically involves a combination of histopathology, immunohistochemistry, and molecular testing. Treatment options vary depending on the specific condition and may include surgery, chemotherapy, and radiation therapy.

See Also

• Epithelium
• Granuloma
• Neoplasm
• Carcinoma
• Melanoma
• Sarcoidosis
• Tuberculosis