Desipramine hydrochloride

Desipramine Hydrochloride

Desipramine hydrochloride (pronunciation: de-SIP-ra-meen HYE-droe-KLOR-ide) is a type of tricyclic antidepressant (TCA) primarily used in the treatment of depression and neuropathic pain.

Etymology

The term "desipramine" is derived from its chemical structure, which is a derivative of the parent compound imipramine. The "des-" prefix indicates the removal of a methyl group from the parent compound.

Pharmacology

Desipramine hydrochloride works by inhibiting the reuptake of norepinephrine and, to a lesser extent, serotonin, thereby increasing the levels of these neurotransmitters in the brain. This helps to alleviate symptoms of depression and neuropathic pain.

Related Terms

• Tricyclic antidepressant (TCA)
• Depression
• Neuropathic pain
• Norepinephrine
• Serotonin
• Imipramine

See Also

• List of antidepressants
• List of medications for neuropathic pain

References

• National Institute of Mental Health
• World Health Organization

External links

• Medical encyclopedia article on Desipramine hydrochloride
• Wikipedia's article - Desipramine hydrochloride

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